A Importância da Metrologia e da Normalização no Desenvolvimento e Compatibilidade de Órgãos-em-Chip – Projeto MFMET II
A Importância da Metrologia e da Normalização no Desenvolvimento e Compatibilidade de Órgãos-em-Chip – Projeto MFMET II
A crescente utilização de órgãos-em-chip na biomedicina, indústria farmacêutica e química exige padrões de medição rigorosos. Estes dispositivos simulam funções de órgãos humanos em ambientes controlados, sendo essenciais para testes de medicamentos, estudos toxicológicos e investigação biomédica. Contudo, a falta de normas específicas limita a fiabilidade e a rastreabilidade dos resultados.
O projeto MFMET II – Establishing Metrology Standards in Microfluidic Devices, financiado pela Comissão Europeia através do programa European Partnership on Metrology (EPM) do Horizonte Europa, visa desenvolver normas e metodologias metrológicas para dispositivos microfluídicos, com foco na tecnologia de órgãos- em-chip. Coordenado pelo Instituto Português da Qualidade (IPQ), reúne 19 parceiros, incluindo Institutos Nacionais de Metrologia (INM), Universidades, Centros de Investigação e Indústria.
O projeto propõe protocolos para a medição de grandezas como caudal, pressão, volume, compatibilidade de materiais e controlo da qualidade, além de contribuir para a avaliação da conformidade de dispositivos médicos. Também prevê padrões de transferência microfluídicos para a calibração e validação. Os resultados apoiarão normas internacionais, como as do comité ISO/TC 48/WG 3, garantindo precisão, reprodutibilidade e segurança. Ao promover a Normalização e a Metrologia, o MFMET II reforça a confiança nos órgãos-em-chip e acelera a sua integração em aplicações clínicas e industriais.
Metrologia, microfluídica, normalização, órgãos-em-chip
Elsa Batista has received a PhD from the Faculty of Sciences and Technology – Nova University of Lisbon – Portugal. Since 1999, she has worked at the Laboratório de Volume of Instituto Português da Qualidade as a superior technician and laboratory manager. She is the contact person and head of the volume subgroup of the EURAMET flow technical committee. She is the coordinator of project MFMET II.
Sara Moura has received a postgraduate degree in Management in Quality and Food Safety in 2004 from the Higher Institute of Health Sciences – South; Egas Moniz C.R.L. – Portugal. She is laboratory manager in Properties of Liquids Laboratory of Portuguese Institute for Quality (IPQ), where she works since 2021. Her research interests are in the areas of density, viscosity, surface tension and reology.
Marta Serra has received a MSc in BioChemistry in 2017 from the Faculty of Sciences and Technology – Nova University of Lisbon – Portugal. She is senior technician in Properties of Liquids Laboratory of Portuguese Institute for Quality (IPQ), where she works since 2023. Her research interests are in the areas of density, viscosity, surface tension and reology.
Fernanda Saraiva is M.Sc. in Physics Engineering from the Faculty of Sciences and Technology – Nova University of Lisbon – Portugal since 2019. She is the head of the Metrology Length Laboratory, at the Portuguese Institute for Quality, in Almada, Portugal. The main research interest is measuring techniques, quality assessment, metrological compatibility, and calibration of metrological standards of length.
Maria do Céu Ferreira has a PhD and master’s degree in Industrial Engineering from FCT/UNL and has worked in the metrology department at IPQ as an engineer and metrologist in the scientific, applied, and legal fields. She is also a university lecturer in Industrial Engineering and Management, as well as being the national coordinator of the Metrology Specialisation Committee of the Portuguese Order of Engineers. Maria participates in international research projects in the field of metrology and represents Portugal in ISO, OIML and WELMEC working groups.
Antonio Capela has a degree in science of information and documentation and works in the volume and flow laboratory of IPQ since 2022.
Isabel Godinho has a degree in Physics from the Faculty of Sciences of the University of Lisbon and a PhD in Physics from the same University. She is presently Director of the Metrology Department of IPQ and responsible for the national metrology system, in scientific, applied and legal metrology. She is currently EURAMET delegate and European Partnership on Metrology representative and national representative on the OIML and BIPM. Her research interest is in metrology, mainly in the fields of electrical, quantum metrology and acceleration.
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